Orlando Protocol for single session ductal clearance of common bile duct stones at endosopic retrograde cholangiopancreatography.

Autor: Bang, Ji Young, Wilcox, C. Mel, Navaneethan, Udayakumar, Hawes, Robert, Varadarajulu, Shyam
Předmět:
Zdroj: Digestive Endoscopy; Jul2024, Vol. 36 Issue 7, p825-833, 9p
Abstrakt: Objectives: Approach to management of common bile duct stones (CBDS) by endoscopic retrograde cholangiopancreatography (ERCP) is not standardized. We examined outcomes by applying predetermined protocol for CBDS management. Methods: When standard extraction techniques failed at ERCP, presence of tapered bile duct and stone–duct ratio were calculated. Large balloon sphincteroplasty (LBS) and/or mechanical/single‐operator cholangioscopy‐guided lithotripsy was performed based on presence of tapered bile duct and stone–duct mismatch. Primary outcome was single‐session ductal clearance. Secondary outcome was adverse events. Results: Of 409 patients treated over 16 months, 321 (78.5%) had no tapered bile duct or stone–duct mismatch, and single‐session ductal clearance was achieved using standard techniques in 99.7% over median duration of 14 min (interquartile range [IQR] 9–21 min). Of 88 (21.5%) patients with difficult CBDS, tapered duct was seen in 79 (89.8%) and/or stone–duct mismatch in 36 (40.9%). Single‐session ductal clearance was achieved in all 88 patients (100%) by LBS in 79 (89.8%), mechanical lithotripsy in 20 (22.7%), and single‐operator cholangioscopy‐guided lithotripsy in 16 (18.2%) over a median duration of 29 min (IQR 17–47 min). Overall, single‐session ductal clearance was achieved in 99.8% with adverse events in 17 (4.2%) that included perforation in two, postsphincterotomy bleeding in one, and mild/moderate post‐ERCP pancreatitis in 14 patients. Conclusions: A predetermined protocol optimized outcomes by enabling single‐session ductal clearance of CBDS with high technical success and low adverse events. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index