Reports from Guangdong Medical University Provide New Insights into Heart Attack (Myocardial Infarction Accelerates the Progression of Mash By Triggering Immunoinflammatory Response and Induction of Periostin).

Předmět:
Zdroj: Cardiovascular Week; 7/16/2024, p653-653, 1p
Abstrakt: A study conducted by researchers at Guangdong Medical University in Dongguan, China, has found that myocardial infarction (heart attack) can accelerate the progression of metabolic dysfunction-associated steatohepatitis (MASH), a type of liver disease. The study showed that patients with MASH who experienced cardiovascular disease events after their diagnosis exhibited accelerated liver fibrosis progression. The researchers also found that myocardial infarction promotes hepatic fibrosis in mice with MASH, and that this effect can be mitigated by deleting certain cells. The study suggests that myocardial infarction alters systemic homeostasis and triggers cross-disease communication that accelerates the progression of MASH. [Extracted from the article]
Databáze: Complementary Index