Abstrakt: |
A recent study conducted by the Instituto Nacional de Cardiologia Ignacio Chavez in Mexico City has found that certain microRNAs (miRs) may play a role in the development of complications in patients with type 2 diabetes, specifically diabetic foot ulcers. The study analyzed the expression of miRs in 41 diabetic foot patients and 50 controls, and found that diabetic foot patients had significantly higher levels of miR-17-5p, miR-191-5p, let-7e-5p, and miR-33a-5p compared to controls. The study suggests that high expression of miR-17, miR-191, and miR-121 is strongly associated with higher glucose levels and the development of diabetic foot ulcers. Further research is needed to explore the potential of these miRs as therapeutic targets for more effective treatments. [Extracted from the article] |