| Abstrakt: |
A recent study conducted at Manipal College of Dental Sciences in Karnataka, India, explored the role of microRNAs (miRNAs) in the development of periodontitis (PD) in individuals with diabetes mellitus (DM). The study found that certain miRNAs, such as miRNA-146a and miRNA-155, were associated with PD in individuals with DM. These miRNAs impact immune mechanisms, oxidative stress, hyperglycemia, and insulin sensitivity, contributing to periodontal destruction in DM. However, the clinical utility of miRNAs as biomarkers for PD and DM is limited due to the lack of standardized tests. Further research is needed to identify specific miRNAs for DM-associated PD through human studies and to standardize sample collection and detection methods. [Extracted from the article] |
