| Abstrakt: |
A recent study conducted by researchers at the Medical University of South Carolina has shed light on the limited regenerative ability of mammalian cardiomyocytes, which are heart muscle cells. The study focused on the role of ferroptosis, a specific form of regulated cell death, in cardiomyocyte death and heart regeneration. The researchers found that inhibiting ferroptosis did not improve heart regeneration and actually compromised cardiac function. Additionally, they discovered that ferroptotic cardiomyocytes released pro-angiogenic factors that supported wound healing. These findings provide insights into the mechanisms of cardiomyocyte death and may guide the development of therapies for heart disease. [Extracted from the article] |
