| Abstrakt: |
A recent study conducted in Basra, Iraq, focused on hemophagocytic lymphohistiocytosis (HLH), a life-threatening syndrome characterized by fever, cytopenia, and organomegaly. The study included 34 pediatric and adult patients with HLH and 34 healthy individuals as a control group. The researchers found that HLH patients had significantly lower hemoglobin levels and platelet counts, as well as higher levels of serum ferritin and triglycerides. Additionally, genetic testing revealed that 38.8% of the tested subjects had mutations in the perforin gene. The study emphasizes the importance of early diagnosis and referral to hematopoietic stem cell transplantation for infants with familial HLH. [Extracted from the article] |
