| Autor: |
Dubey, Debasmita, Meher, Rajesh Kumar, Pradhan, Biswaranjan, Induar, Sadhni, Kar, Biswakanth, Naik, Pradeep Kumar, Chandra Behera, Bikash |
| Předmět: |
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| Zdroj: |
Journal of Chemical Technology & Biotechnology; Aug2024, Vol. 99 Issue 8, p1743-1753, 11p |
| Abstrakt: |
BACKGROUND: Woodfordia fruticosa is a well‐known medicinal plant traditionally used for various treatment methods. Green synthesis of silver nanocomposite with woodfordia flower extract is well‐investigated. However, the therapeutic potential of Woodfordia fruticosa leaf extract silver nanoparticles against various diseases has yet to be investigated. RESULTS: Silver nanoparticles synthesized from Woodfordia fruticosa leaf extract (Wf‐AgNPs) showed UV spectral peaks at 450 nm. Transmission electron microscope (TEM) images, ranging from 20 to 50 nm, confirm the nanosynthesis. The average particle size of 39.63 nm with a zeta potential distribution value 17.0 was observed. Fourier transform infrared peaks ranging from 2942to 669 cm−1 confirm the amines, amides, carboxylic, aldehyde, alkane, phenolic and aliphatic bromo compounds involved in the synthesis of AgNPs. Wf‐AgNPs showed higher antioxidant activity compared to the ascorbic acid and BHT. The phenolic and flavonoid content was 141.66 ± 8.50 mg GAE/100 g dry weight and 191.66 ± 5.6 mg quercetin equivalent/100 g dry weight, respectively. Wf‐AgNPs showed a strong inverse relationship between the dose and viability of the cancer cells. The antibacterial properties of Wf‐AgNPs were confirmed through the bacteria's SEM images. Increased wound healing potential, re‐epithelization and elevation of the tensile strength of the infected skin tissue were observed after applying synthesized Wf‐AgNPs. CONCLUSION: Various phytochemicals in the synthesized nanoparticles confer antimicrobial, antioxidant, anticancer and wound‐curing potentiality to the Wf‐AgNPs. © 2024 Society of Chemical Industry (SCI). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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