| Abstrakt: |
Jasminum subtriplinerve, a Southeast Asia medicinal plant, is traditionally used in Vietnam for its anti-inflammatory, pain-relieving, and antioxidant activity. This study investigates the potential of J. subtriplinerve extracts from the leaf and stem, green fruit, and ripe fruit (obtained from different biological cultivation locations) to inhibit nitric oxide (NO) production and scavenge DPPH radicals. Results reveal significant variations in IC50 values among different plant parts and cultivation locations. The results show that the leaf and stem extracts demonstrated the most potent inhibition of NO production, with the lowest IC50 value observed in Dong Giang (72.46 μg/mL). Conversely, the green and ripe fruit extracts showed weak inhibitory effects, with IC50 values exceeding 90 μg/mL in most cases. Furthermore, analysis of scavenging activity against free radicals using DPPH assay showed similar trends, with the leaf and stem extract exhibiting more potent inhibitory activities than fruit extracts. SC50 values for LS extracts ranged from 36.83 to 50.95 μg/mL. In contrast, GF and RF extracts exhibited weak antioxidant activity, SC50 values exceeding 60 μg/mL, and, in some cases, negligible biological activity (>100 μg/mL). These findings underscore the importance of considering both the plant part and the cultivation location when evaluating the efficacy of J. subtriplinerve extracts in modulating NO production and antioxidant activity. [ABSTRACT FROM AUTHOR] |
