Toll Like Receptor 4 Gene in Triple Breast Cancer: Prognostic Relevance.

Autor:	Salunke, Rushigandha, Jhondale, Mayur, Saldhana, Elveera, Joshi, Shalaka, Sahay, Ayushi, Chandrani, Pratik, Mukherjee, Nupur
Předmět:	BRCA genes TRIPLE-negative breast cancer INDIAN women (Asians)
Zdroj:	Indian Journal of Medical & Paediatric Oncology; 2024 Supplement 1, Vol. 45, pS1-S16, 16p
Abstrakt:	This article, titled "Toll Like Receptor 4 Gene in Triple Breast Cancer: Prognostic Relevance," explores the role of Toll-like receptor 4 (TLR4) in the pathogenesis of triple-negative breast cancer (TNBC). TNBC is a subtype of breast cancer that lacks certain receptors and accounts for a significant percentage of cases in Indian women. The study examines the expression of TLR4 pathway-associated genes in TNBC tumors and validates the findings using a TNBC transcriptome dataset. The results suggest a synergistic association between TLR4 and IFNϒ signaling in the development of TNBC. [Extracted from the article]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.