Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses.

Autor:	Ragland, Stephanie A., Kagan, Jonathan C.
Předmět:	SINGLE-stranded DNA IMMUNE response RIBONUCLEASES CELL death EXONUCLEASES
Zdroj:	Science Immunology; 2024, Vol. 9 Issue 96, p1-3, 3p
Abstrakt:	Single-stranded DNA containing CGT/A motifs binds to the helicase domain of Schlafen 11 (SLFN11) to initiate cell death and cytokine production via SLFN11 ribonuclease activity (see related Research Article by Zhang et al.). [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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