| Autor: |
Hollenbeak, Christopher S., Duan, Fenghai, Subramaniam, Rathan M., Taurone, Alexander, Sicks, JoRean, Lowe, Val J., Stack, Brendan C. |
| Předmět: |
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| Zdroj: |
Head & Neck; Aug2024, Vol. 46 Issue 8, p1988-1998, 11p |
| Abstrakt: |
Background: This study examined the trajectory of health‐related quality of life (HRQoL) for patients with clinical stage N0 HNSCC enrolled in ACRIN 6685 who underwent elective neck dissection(s). Methods: HRQoL of 230 patients in the ACRIN 6685 trial was measured prospectively up to 2 years following surgery using the University of Washington Quality of Life instrument. Results: General Health Within the Last 7 Days did not differ significantly from baseline at any follow‐up. General Health Relative to Before Cancer fell significantly by 5.8 points following surgery (p = 0.048), and then returned to 3.0 points above baseline at 1 year (p = 0.65). For Overall Quality of Life, HRQoL fell significantly by 4.3 points following surgery (p = 0.031) and then returned to levels not significantly different from baseline. Conclusions: Patients with stage N0 HNSCC experience significant declines in HRQoL immediately following surgery, including neck dissection, which recovers to near or better than baseline within 1–2 years. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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