OUTBREAK INVESTIGATION OF VARICELLA-ZOSTER AMONG HOSTEL INMATES AT TERTIARY CARE CENTRE, KALABURAGI, KARNATAKA: A CASECONTROL STUDY.

Autor: S., Sangita, H., Ramesh, Anandi, Basavakumar, N. A., Gururaj, G., Ajaykumar, Kalasker, Pavan S.
Předmět:
Zdroj: International Journal of Medicine & Public Health; Apr-Jun2024, Vol. 14 Issue 2, p223-227, 5p
Abstrakt: Background: Varicella (chickenpox) is a febrile rash illness resulting from a primary infection with the varicella-zoster virus (VZV). The disease is more prevalent in children than adults. Adults when affected manifest severe symptoms. Material and Methods: Following a sudden increase in cases in April 2023, an outbreak investigation and a matched case-control study were conducted, to assess the risk of varicella transmission among hostel inmates of a tertiary care center in Kalaburagi. Based on the clinical diagnosis, 8 cases and 32 controls matched for gender and year of course were chosen. The survey was conducted using an epidemiological case sheet, containing students' sociodemographic profile and clinical history, after obtaining written consent. Data was entered in an Excel sheet and analysed using JAMOVI software. The outbreak was described in terms of time, place, and person using descriptive statistics. The odds ratio was calculated to assess the strength of the association between risk factors and varicella infection. Results: The index case, 22 years old was detected on 7th April, 2023 in boys hostel following which 7 more students were affected with a secondary attack rate of 6.93%. Mean (SD) age of cases was 20.13(1.36) years and males (75%) were most commonly affected. Majority (62.5%) presented with moderate lesions with none developing complications. All cases were identified and isolated (mean duration of 12.75(3.93) days) with strict precautions. Personal protective measures usage was significantly protective against varicella among risk factors, with an odds ratio of 0.09 (95% CI 0.01,0.51). Conclusion: With the help of active case finding, isolation, and vaccination campaigns, the outbreak was successfully controlled. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index