| Autor: |
Jaafar, Norliana, Mohamad, Ikhwan Sani, Fathi Mohammad Azmi, Mohd Azem, Mohd Shah, Mohd Shahrulsalam, Nadarajan, Chandran, Yusoff, Bazli Md, Husin, Mohd Hafizuddin, Leow Voon Meng |
| Předmět: |
|
| Zdroj: |
Surgical Chronicles; Jan-Mar2024, Vol. 29 Issue 1, p61-67, 7p |
| Abstrakt: |
Background and objectives: Trans Arterial Chemo Embolisation (TACE) is the treatment choice for most unresectable hepatocellular carcinoma (HCC) patients. Post-embolisation syndrome (PES) is the most common complication. PES definition was a constellation of fever, nausea/vomiting, and abdominal pain within the first 72 hours post-TACE regardless of the need for systemic medication. This study aims to identify the risk factors of PES and its association with patients' survival. Variables included demographic, clinical characteristics, tumour characteristics and procedure characteristics were identified. Study design and method: This is a retrospective study in a single centre, Hospital Universiti Sains Malaysia, Kelantan. This study showed that 90 HCC patients underwent TACE procedures between 1st January 2016 and 31st December 2019. Variables included demographic, clinical characteristics, tumour characteristics and procedure characteristics were collected. Data were entered and analysed using Statistical Package for the Social Sciences (SPSS) version 22. Results: The prevalence of PES among 90 patients was 25.6% (n = 23). There was a significant association between related variables towards PES, such as the number of tumours (p = 0.039), lobar involvement (p = 0.024) and chemotherapy type (p = 0.035) when adjusted for other variables. Also, there was a significant association between PES and survival duration (p = 0.001). Majority of the patients with no PES found highest in the group of survival duration of more and equal to 12 months (n = 56, 62.2%). Conclusion: We found that PES is a clinically significant event in HCC patients. There were few risk factors identified in this study. PES is associated with a worse prognosis in terms of survival rate for patients who experience it. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
