Research on Nanopharmaceuticals Reported by Researchers at I.M. Sechenov First Moscow State Medical University (Cerium Dioxide-Dextran Nanocomposites in the Development of a Medical Product for Wound Healing: Physical, Chemical and Biomedical...).

Předmět:
Zdroj: Medical Imaging Week; 7/14/2024, p2444-2444, 1p
Abstrakt: Researchers at I.M. Sechenov First Moscow State Medical University in Russia have conducted a study on nanopharmaceuticals for wound healing. The study aimed to create nanocomposites by coating cerium oxide crystals with dextran and determine the best nanocomposite for developing a nanodrug that promotes wound healing and has antimicrobial effects. The researchers synthesized nanocomposites using different ratios of cerium nitrate and dextran and conducted various physicochemical experiments to characterize the nanocomposites. They found that nanocrystals less than 5 nm in size with cerium dioxide characteristics were present in all synthesized nanocomposites, and the smallest nanoparticles were found in certain composites. Cell experiments showed the safety and effectiveness of the nanocomposites, with certain composites enhancing cell proliferation and metabolism. The researchers also observed antimicrobial activity against E. coli. Based on their findings, they selected a specific nanocomposite for further development of a nanodrug. [Extracted from the article]
Databáze: Complementary Index