Reports Outline Type 2 Diabetes Research from Ruhr-University Bochum (Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in...).

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Zdroj: Diabetes Week; 7/8/2024, p281-281, 1p
Abstrakt: A recent report from Ruhr-University Bochum in Germany explores the relationship between type 2 diabetes (T2D) and Alzheimer's disease (AD). The study focuses on the effects of T2D on the hippocampus, a region of the brain associated with memory and learning. The researchers found that T2D-like conditions in an animal model led to decreased hippocampal volume, impaired synaptic plasticity, and increased vulnerability to amyloid-beta, a hallmark of AD. The study suggests that changes in amylin receptor signaling may play a role in these effects. Further research is needed to better understand the connection between T2D and AD. [Extracted from the article]
Databáze: Complementary Index