Abstrakt: |
Researchers at Pontifical Catholic University of Parana (PUCPR) in Curitiba, Brazil, have conducted a study on tissue engineering for tracheal defects. The study focused on the potential therapeutic implants of decellularized Wharton's Jelly (WJ) and amniotic membrane (AM) in rabbits. After 60 days of implantation, the researchers found that while both scaffolds showed biocompatibility and a favorable microenvironment for cell survival, they did not demonstrate significant histopathological benefits in tracheal tissue regeneration. This research provides insights into the challenges and potential alternatives for tracheal reconstruction surgery. [Extracted from the article] |