| Abstrakt: |
A report from researchers at the University of Technology Sydney discusses the cytotoxicity of acridinium-based ionic liquids (ILs) and their potential as novel anticancer agents. The study found that acridinium-based ILs containing large cations were potent cytotoxic agents, reducing the viability of breast cancer cells. Unlike a pyridinium-based analogue, the acridinium-based ILs did not inhibit oxidative phosphorylation or induce reactive oxygen species formation, suggesting they may target other mitochondrial processes or components. This research provides insights into the structural features that promote IL cytotoxicity and opens up possibilities for the development of new anticancer treatments. [Extracted from the article] |
