Research from Albert Einstein College of Medicine Yields New Data on Influenza (Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase).

Předmět:	BISPECIFIC antibodies INFLUENZA viruses NEURAMINIDASE INFLUENZA BLOOD proteins
Zdroj:	Immunotherapy Weekly; 7/9/2024, p2278-2278, 1p
Abstrakt:	A recent study conducted by researchers at Albert Einstein College of Medicine has explored the potential of bispecific antibodies (bsAbs) in the prevention and treatment of influenza virus infection. The study focused on the development of bsAbs that simultaneously target two glycoproteins on the influenza virion surface: hemagglutinin (HA) and neuraminidase (NA). The researchers found that these bsAbs showed potent neutralizing and egress-inhibiting activity, providing higher levels of prophylactic protection from mortality and morbidity compared to parental monoclonal antibodies. This research highlights the potential use of bsAbs as new influenza immunotherapeutics, offering enhanced activity in combating the global health burden of influenza. [Extracted from the article]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu