| Autor: |
He, Yongjun, He, Tian-Juan, Cheng, Xiufang, Wei, Yibo, Wang, Huamin, Lin, Ying-Wu |
| Předmět: |
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| Zdroj: |
Chemical Communications; 7/11/2024, Vol. 60 Issue 54, p6961-6964, 4p |
| Abstrakt: |
An efficient phosphine-catalyzed dearomative [3+2] annulation of 4-nitroisoxazoles with allenoates or Morita–Baylis–Hillman carbonates has been established for the convenient synthesis of bicyclic isoxazoline derivatives. This reaction approach showed a broad substrate scope, high functional group compatibility, and excellent regioselectivity and diastereoselectivity. Furthermore, the success at the gram-scale and synthetic applications of the obtained compound 3a demonstrate the great potential of this methodology for practical applications in organic synthesis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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