| Autor: |
Attah, Abraham, Peterson, Chelsea, Jacobs, Max, Bhagavatula, Rama, Shah, Deep, Kaplan, Robert, Samhouri, Yazan |
| Předmět: |
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| Zdroj: |
Hematology Reports; Jun2024, Vol. 16 Issue 2, p295-298, 4p |
| Abstrakt: |
Heparin products are frequently used in the inpatient setting to prevent and treat venous thromboembolism, but they simultaneously put patients at risk of developing heparin-induced thrombocytopenia (HIT). The 4Ts score determines the pretest probability of HIT. Diagnosis is made with a screening antiplatelet factor (PF4) immunoassay and the serotonin-release assay (SRA) as a confirmatory test. Anti-PF4 assays have high sensitivity (98%) but lower specificity (50%) and result in frequent false-positive tests. We present a rare case from our institution of a patient with anti-PF4–Polyanion ELISA-negative, SRA-positive HIT and describe the challenges in making a timely diagnosis in this case. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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