| Autor: |
Yang, Jing, Hu, Xing-Mei, Zhao, Ke-Hua, Huang, Kun, Yan, Sheng-Jiao |
| Předmět: |
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| Zdroj: |
New Journal of Chemistry; 7/14/2024, Vol. 48 Issue 26, p11682-11687, 6p |
| Abstrakt: |
A novel synthesis method has been developed for the construction of functionalized 2,4-diarylpyridines. The reaction involves several key processes, including a reduction reaction, Michael reaction, decarboxylation, intramolecular cyclization, oxidation, ring-opening and aromatization reaction. All of these processes are facilitated by heating a mixture of the starting materials in an environmentally benign solvent, propylene carbonate (PC), with the oxidant (air) and the catalyst Cu(OAc)2. This cascade reaction not only forms two new bonds but also cleaves three existing bonds in a single pot. The protocol presented in this study is a valuable tool for synthesizing functionalized unsymmetrical 2,4-diarylpyridines. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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