Ability of Hypocaloric Diets to Change Nutrient–Phyla Associations after 8 Weeks of Intervention.

Autor: Noronha, Natália Yumi, Martins, Luzânia dos Santos, Watanabe, Lígia Moriguchi, de Souza Pinhel, Marcela Augusta, Rodrigues, Guilherme da Silva, Schneider, Isabelle Mello, Nicoletti, Carolina Ferreira, Delfino, Heitor Bernardes Pereira, Carlos, Daniela, Nonino, Carla Barbosa
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Zdroj: Obesities; Jun2024, Vol. 4 Issue 2, p45-54, 10p
Abstrakt: Background: Previous studies have suggested that changes in the composition of intestinal microbiota may be influenced by dietary quality. Objective: This study aimed to assess the impact of a hypocaloric diet on the relationship between microbiota and clinical/dietary variables. Methods: This was a longitudinal study. Ten women with obesity (Obese Group, ObG) participated in an 8-week home-based hypocaloric diet intervention. Anthropometric, dietary intake, biochemical, and gut microbiota assessments were conducted before and after the intervention. Microbiota relative abundance was determined using real-time PCR in triplicate. Results: In the ObG, the hypocaloric diet intervention led to significant weight loss (before: 119.5 ± 10.3 kg; after: 114.9 ± 10.2 kg; p = 0.003). Following the intervention, positive correlations were observed between nutrient intake and phyla composition: Actinobacteria phylum with fibers (r = 0.787; p = 0.012), Firmicutes phylum with proteins (r = 0.736; p = 0.024), and Proteobacteria phylum with lipids (r = 0.669; p = 0.049). Conclusions: The hypocaloric diet intervention improved health parameters associated with obesity and its comorbidities, demonstrating associations between nutrient intake and specific phyla. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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