| Autor: |
Ghaffar, Usman, E Habiba, Umm, Majeed, Muhammad Irfan, Nawaz, Haq, Rashid, Nosheen, Akhtar, Nasrin, Ahmad, Abdullah, Tahir, Muhammad, Naman, Abdul, Tabussam, Tania, Ishtiaq, Shazra, Zafar, Fareeha, Hajab, Hawa |
| Předmět: |
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| Zdroj: |
Analytical Letters; 2024, Vol. 57 Issue 14, p2182-2199, 18p |
| Abstrakt: |
Surface-enhanced Raman spectroscopy (SERS) was employed to detect the biochemical changes in Gordonia-HS126-4N bacterial strain mediated by exposure to 4,6-dimethyldibenzothiophene. SERS has revealed significant changes induced in the bacterial cells after exposure to a compound, confirming its potential for evaluating their desulfurization capability. Principal component analysis (PCA) and partial least squares–discriminant analysis (PLS-DA) were demonstrated to be effective tools for comparison of the exposed and unexposed bacterial strains. PCA was used for differentiating the SERS spectra of unexposed and exposed Gordonia-HS126-4N. PLS-DA was employed on SERS spectra for the discrimination of the unexposed and exposed bacterial strains with 87% specificity, 88% sensitivity, 89% accuracy, and the value of area under the receiver operating characteristics curve (AUROC) of 0.78, which indicates the excellent performance of the chemometric model. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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