Relationship between Baseline Serum Potassium and 1-Year Readmission in Pediatric Patients with Heart Failure: A Retrospective Cohort Study.
| Autor: | Han, Yong, Huang, Yuqin, Su, Danyan, Liu, Dongli, Chen, Cheng, Pang, Yusheng |
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| Předmět: |
RISK assessment
RECEIVER operating characteristic curves POTASSIUM PATIENT readmissions HYPERKALEMIA KRUSKAL-Wallis Test HEART failure RETROSPECTIVE studies DESCRIPTIVE statistics CHI-squared test LONGITUDINAL method KAPLAN-Meier estimator LOG-rank test MEDICAL records ACQUISITION of data ONE-way analysis of variance CONFIDENCE intervals DATA analysis software TIME REGRESSION analysis PROPORTIONAL hazards models DISEASE complications CHILDREN |
| Zdroj: | Children; Jun2024, Vol. 11 Issue 6, p725, 10p |
| Abstrakt: | Pediatric heart failure (HF) is associated with high readmission rates, but the optimal serum potassium range for this population remains unclear. In this single-center retrospective cohort study, 180 pediatric patients hospitalized for HF between January 2016 and January 2022 were stratified into low-potassium (<3.7 mmol/L), middle-potassium (3.7–4.7 mmol/L), and high-potassium (≥4.7 mmol/L) groups based on the distribution of potassium levels in the study population. The primary outcome was readmission for HF within 1 year of discharge. Cox regression and restricted cubic spline models were used to assess the association between potassium levels and 1-year HF readmission rates. Notably, 38.9% of patients underwent 1 or more 1-year readmissions for HF within 1 year. The high-potassium group had a significantly higher readmission frequency than the middle-potassium group. In multivariate Cox regression models, potassium levels of ≥4.7 mmol/L were independently associated with increased 1-year readmission risk. A J-shaped relationship was observed between baseline potassium levels and 1-year readmission risk, with the lowest risk at 4.1 mmol/L. In pediatric patients with HF, a serum potassium level ≥ 4.7 mmol/L was independently associated with increased 1-year readmission risk. Maintaining potassium levels within a narrow range may improve outcomes in this population. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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