Validation of continuous intraabdominal pressure measurement: feasibility and accuracy assessment using a capsular device in in-vivo studies.

Autor:	Ho, Dong-Ru, Cheng, Chi-Tung, Ouyang, Chun-Hsiang, Lin, Wei-Cheng, Liao, Chien-Hung
Předmět:	SWINE STATISTICAL correlation RESEARCH funding RESEARCH evaluation PILOT projects DIGITAL health TREATMENT effectiveness IN vivo studies DESCRIPTIVE statistics INTRA-abdominal hypertension INTRA-abdominal pressure CAPSULE endoscopy ANIMAL experimentation CATHETERS CARBON dioxide COMPARATIVE studies PATIENT monitoring ANESTHESIA CRITICAL care medicine EVALUATION
Zdroj:	World Journal of Emergency Surgery; 6/26/2024, Vol. 19 Issue 1, p1-7, 7p
Abstrakt:	Background: Monitoring Intraabdominal Pressure (IAP) is essential in critical care, as elevated IAP can lead to severe complications, including Abdominal Compartment Syndrome (ACS). Advances in technology, such as digital capsules, have opened new avenues for measuring IAP non-invasively. This study assesses the feasibility and effectiveness of using a capsular device for IAP measurement in an animal model. Method: In our controlled experiment, we anesthetized pigs and simulated elevated IAP conditions by infusing CO2 into the peritoneal cavity. We compared IAP measurements obtained from three different methods: an intravesical catheter (IAPivp), a capsular device (IAPdot), and a direct peritoneal catheter (IAPdir). The data from these methods were analyzed to evaluate agreement and accuracy. Results: The capsular sensor (IAPdot) provided continuous and accurate detection of IAP over 144 h, with a total of 53,065,487 measurement triplets recorded. The correlation coefficient (R²) between IAPdot and IAPdir was excellent at 0.9241, demonstrating high agreement. Similarly, IAPivp and IAPdir showed strong correlation with an R² of 0.9168. Conclusion: The use of capsular sensors for continuous and accurate assessment of IAP marks a significant advancement in the field of critical care monitoring. The high correlation between measurements from different locations and methods underscores the potential of capsular devices to transform clinical practices by providing reliable, non-invasive IAP monitoring. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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