| Autor: |
Unmuth, Laura, Lipinski, Britta, Pekar, Lukas, Evers, Andreas, Elter, Desislava, Zielonka, Stefan |
| Zdroj: |
BioSpektrum; Jun2024, Vol. 30 Issue 4, p460-461, 2p |
| Abstrakt: |
Antibody-based cytokine mimetics emerged as promising entities in order to modulate an immune response. These surrogate agonists are bi- and multifunctional antibody-derived molecules that mimic the function of a cytokine by agonizing a specific cytokine receptor. Due to the high modularity of antibody-based building blocks, cytokine functionalities can be highly engineered, for instance with regards to signalling strength and bias. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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