Abstrakt: |
A recent report from the Medical University of Bialystok in Poland explores the potential therapeutic applications of apigenin, a naturally derived flavonoid, in breast cancer treatment. The researchers found that apigenin has a dose-dependent cytotoxic and anti-migratory impact on breast cancer cells. Additionally, the study suggests that apigenin and the chemotherapeutic drug doxorubicin may interact primarily at the level of ATP-binding cassette transporter proteins, with potential influences from the AKT and MYC signaling pathways. These findings highlight the importance of understanding the nuanced interactions between apigenin and conventional chemotherapeutic drugs for more effective cancer treatment strategies. [Extracted from the article] |