Reports Summarize Acute Lymphoblastic Leukemia Study Results from University of Birmingham (The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival).

Předmět:	LYMPHOBLASTIC leukemia ACUTE leukemia DIAMINO amino acids ASPARTIC acid GLUTAMIC acid
Zdroj:	Hematology Week; 7/2/2024, p2136-2136, 1p
Abstrakt:	A recent report from the University of Birmingham discusses the findings of a study on T-cell acute lymphoblastic leukemia (T-ALL), a type of cancer that affects the immune system. The researchers aimed to identify new therapeutic targets for T-ALL treatment by analyzing gene expression and metabolism in T-ALL cells. They discovered that glutamine uptake is crucial for T-ALL cell proliferation and that the glutamate-aspartate transporter EAAT1 plays a key role in converting glutamine to aspartate and nucleotides. The study concludes that EAAT1 could be a potential therapeutic target for T-ALL treatment. [Extracted from the article]
Databáze:	Complementary Index
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