Abstrakt: |
A new study conducted by researchers at Southeast University in Jiangsu, China, explores the potential of using a nanocomposite called ApoE-UPGs-DHA to enhance the treatment of glioblastoma (GBM), a type of brain cancer. The nanocomposite combines near-infrared (NIR)-induced ferrous ion regeneration with DHA, a ferroptosis inducer, to promote cell death in GBM cells. The researchers found that ApoE-UPGs-DHA demonstrated good targeting ability and enhanced toxicity to GBM cells when combined with NIR irradiation. This study suggests that the nanocomposite could be a promising alternative treatment strategy for GBM. [Extracted from the article] |