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| Zdroj: |
TB & Outbreaks Week; 7/5/2024, p833-833, 1p |
| Abstrakt: |
Researchers from the Technical University Munich (TU Munich) have made advancements in understanding the Epstein-Barr virus (EBV). The study focused on identifying differences in the cellular immune response of patients with different EBV-associated diseases or different courses of the same disorder. Three novel EBV-derived antigen formulations were tested in pediatric patients with EBV-associated infectious mononucleosis, and all three formulations enabled the detection of EBV-reactive T cells without prior T-cell expansion in vitro. The findings suggest that these antigen formulations can be used to monitor EBV-specific T-cell responses and identify functional T-cell signatures linked to disease development and severity. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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