Data on Cancer Discussed by Researchers at School of Medical Sciences (Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection).

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Zdroj: Cancer Weekly; 7/2/2024, p251-251, 1p
Abstrakt: A recent report from researchers at the School of Medical Sciences in Manchester, United Kingdom discusses the therapeutic targeting of DNA repair pathways in cancer treatment. The researchers focused on a small molecule called UNC3866, which targets CBX4, a protein involved in DNA repair. They found that treatment with UNC3866 sensitizes certain types of cancer cells to radiation, while being non-toxic to other cells. This research suggests that UNC3866 could be a potential treatment option for HR-ineffective cancers. [Extracted from the article]
Databáze: Complementary Index