Universidade de Brasilia Researcher Furthers Understanding of Herpes Simplex Virus 1 (Antiviral Activities of Mastoparan-L-Derived Peptides against Human Alphaherpesvirus 1).

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Zdroj: Drug Week; 7/5/2024, p3481-3481, 1p
Abstrakt: Researchers at the Universidade de Brasilia in Brazil have conducted a study on the antiviral properties of mastoparans, which are peptides derived from Vespula lewisii venom, against herpes simplex virus 1 (HSV-1). The study found that mastoparan-L and mastoparan-MO exhibited high cell viability and over 80% inhibition of HSV-1, with up to 99% viral replication inhibition. Structural analysis suggested that mastoparans disrupt viral particles before cell attachment. The researchers concluded that mastoparans show promise for controlling HSV-1 infections, but further investigation is needed. [Extracted from the article]
Databáze: Complementary Index