| Autor: |
Holanda, Ingrid Rocha Meireles, de Almeida Corrêa Alfredo, Melissa, Cassiano, Daniel Pinho, Esposito, Ana Cláudia Cavalcante, Lima, Paula Basso, Bagatin, Edileia, Miot, Hélio Amante |
| Předmět: |
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| Zdroj: |
Journal of the European Academy of Dermatology & Venereology; Jul2024, Vol. 38 Issue 7, pe607-e609, 3p |
| Abstrakt: |
A double-blind, randomized, placebo-controlled clinical trial was conducted to assess the efficacy of oral 5mg melatonin in treating facial melasma in women. Fifty adult women with moderate to severe melasma were enrolled and randomly assigned to take either oral melatonin or a placebo for 8 weeks. The primary outcome, the change in Modified Melasma Area Severity Score (mMASI), showed a 22% decrease in the melatonin group compared to a 12% decrease in the placebo group. However, there was no significant difference in the improvement of quality of life scores between the two groups. The study suggests that oral melatonin may have a slight improvement in treating facial melasma, but further research is needed to optimize its benefits and prevent relapse post-treatment. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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