An efficient, step-economical synthesis of β-carboline tethered imidazopyrido[3,4-b]indoles from acetals.

Autor: Vaishali, Banyal, Naveen, Sharma, Shubham, Singh, Manpreet, Malakar, Chandi C., Singh, Virender
Předmět:
Zdroj: New Journal of Chemistry; 7/7/2024, Vol. 48 Issue 25, p11394-11406, 13p
Abstrakt: An efficient one-pot pseudo three component cascade annulation reaction has been devised to generate the fluorescent β-carboline tethered imidazopyrido[3,4-b]indole derivatives. These scaffolds were afforded in high yields via one-pot cascade reaction of diversified β-carboline acetals with NH4Cl through the formation of three C–N bonds in a single operation. The current protocol is step-economical and offers high atom-economy, short reaction time and high structural diversity with excellent yields (57–90%). The synthesized compounds displayed promising photophysical properties and delivered luminescence quantum yield (ΦF) up to 55%. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index