Chemoselective oxidation of aromatic aldehydes to carboxylic acids: potassium tert-butoxide as an anomalous source of oxygen.

Autor: Lone, Waseem I., Rashid, Auqib, Bhat, Bilal A., Rashid, Showkat
Předmět:
Zdroj: Chemical Communications; 6/28/2024, Vol. 60 Issue 51, p6544-6547, 4p
Abstrakt: Chemoselective oxidation of aromatic and heteroaromatic aldehydes (>45 examples) to their corresponding carboxylic acids has been developed. Potassium tert-butoxide acts as an oxygen source during this transformation that delivers the corresponding acids without chromatographic purifications. The use of bench-top reagents, operational simplicity, and high level of chemo-selectivity with respect to oxidation of the least preferred aldehyde functionality, in the presence of more susceptible functional groups, are some of the highlights of this strategy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index