Předmět: |
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Zdroj: |
Zika & Mosquito Week; 6/28/2024, p20-20, 1p |
Abstrakt: |
A recent study conducted in Yaounde, Cameroon investigated the relationship between gamma delta T cell phenotype change and Placental Malaria (PM) with pregnancy outcomes. The study found that placental Plasmodium falciparum infection was associated with an increase in the frequency of total gamma delta T cells and the V delta 1(+) subset, but a decrease in the frequency of the V delta 2(+) subset. The expression of activation and exhaustion markers within gamma delta T cells and subsets were also up-regulated in PM-positive women. These findings suggest that activated and exhausted gamma delta T cells play a role in Plasmodium falciparum placental malaria and can impact pregnancy outcomes such as maternal hemoglobin levels and birth weight. [Extracted from the article] |
Databáze: |
Complementary Index |
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