| Abstrakt: |
New research on colon cancer has found that the inactivation of KDM6A, a protein involved in gene regulation, promotes the progression of colorectal cancer. The study used animal models to demonstrate that knocking out KDM6A expression increased the development of colorectal cancer. The researchers also discovered that KDM6A interacts with HIF-1a, a protein involved in cellular metabolism, and knocking down KDM6A promoted the expression of LDHA, a gene involved in glycolysis. The findings suggest that restoring the function of KDM6A could be a potential strategy for treating colorectal cancer. [Extracted from the article] |
