| Abstrakt: |
A recent study conducted in Binzhou, China, aimed to improve understanding of osteosarcoma (OS), the most common primary malignant bone tumor in children and adolescents. The researchers used bioinformatics tools and datasets to analyze biomarkers related to OS metastasis and prognosis. They identified 701 differentially expressed genes (DEGs) and performed gene ontology and pathway enrichment analyses on the DEGs. Thirteen hub genes were selected from the protein-protein interaction network, and six survival-related genes were identified. The researchers established a prognostic model that suggested four genes (TPM1, TPM2, TPM3, and TPM4) strongly associated with the prognosis of OS. [Extracted from the article] |
