| Autor: |
Pantic, Nikola, Cvetkovic, Mirjana, Milin-Lazovic, Jelena, Vukmirovic, Jelica, Pavlovic, Aleksandar, Virijevic, Marijana, Pravdic, Zlatko, Kozarac, Sofija, Sabljic, Nikica, Suvajdzic-Vukovic, Nada, Dragas, Marko, Mitrovic, Mirjana |
| Předmět: |
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| Zdroj: |
Vascular Medicine; Jun2024, Vol. 29 Issue 3, p320-327, 8p |
| Abstrakt: |
Inferior vena cava (IVC) anomalies are uncommon congenital causes of deep vein thrombosis (DVT). KILT syndrome (kidney and IVC abnormalities with leg thrombosis) has only been described as case reports in the literature. Therefore, the characteristics, evaluation, and management of patients with KILT syndrome have not yet been standardized. This study aimed to systematically review and analyze the clinical and radiographic data and treatment of previously reported cases of KILT syndrome. In this systematic review, we performed a literature search of the PubMed, Scopus, and Web of Science databases in December 2023, with no restrictions on the publication date. After duplicate extractions, 4195 articles were screened. Case reports and case series reporting on KILT syndrome were included. In addition to previously published cases, we included a new case of a previously healthy 25-year-old man with KILT syndrome in the analysis. A total of 34 cases were therefore included in this study. The majority (76.5%) were male patients with a median age of 24 years. In most patients, unprovoked bilateral iliofemoral thrombosis was diagnosed, and 64.7% had left kidney abnormalities. Our study suggests that anomalies of the IVC should be suspected in all young patients, especially male patients, with proximal, recurrent, or idiopathic DVT. If an IVC anomaly is confirmed, the kidneys should be examined to monitor and preserve healthy kidneys in cases of KILT syndrome. The data collected from all patients emphasize the requirement of long-term anticoagulation and risk factor control. Surgical measures may be effective for treating symptomatic refractory cases. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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