Is eGFR ≥60 mL/min/1.73 m 2 in Patients Undergoing Coronary Angiography Really Safe for Contrast Nephropathy?

Autor:	Comoglu, Mustafa, Acehan, Fatih, Katipoglu, Bilal, Demir, Burak F., Guven Cetin, Zehra, Ates, Ihsan
Předmět:	RISK assessment PATIENT safety SURGERY PATIENTS RECEIVER operating characteristic curves DATA analysis MULTIPLE regression analysis ACUTE kidney failure RETROSPECTIVE studies MULTIVARIATE analysis DESCRIPTIVE statistics LONGITUDINAL method ODDS ratio STATISTICS CORONARY angiography COMPARATIVE studies CONFIDENCE intervals GLOMERULAR filtration rate CONTRAST media DISEASE risk factors
Zdroj:	Angiology; Aug2024, Vol. 75 Issue 7, p666-672, 7p
Abstrakt:	The aim of the present study was to define the risk factors associated with contrast-induced acute kidney injury (CI-AKI) in patients who underwent coronary artery angiography (CAG). In this retrospective cohort study, patients who underwent CAG between March 2014 and January 2022 were evaluated. A total of 2923 eligible patients were included in the study. Univariate and multivariate logistic regression analysis was used to identify the predictive factors. CI-AKI developed in 77 (2.6%) of 2923 patients. In multivariate analysis, diabetes mellitus (DM), chronic kidney disease (CKD), and estimated glomerular filtration rate (eGFR) were found to be independent factors associated with CI-AKI. In the subgroup analysis of patients with eGFR ≥60 mL/min/1.73 m2, eGFR remained a predictor of CI-AKI (Odds ratio (OR):.89, 95% CI:.84-.93; that is, a lower eGFR remains a risk factor for CI-AKI). In the receiving operating characteristic (ROC) analysis of patients with eGFR ≥60 mL/min/1.73 m2, the area under the curve of the eGFR was.826. Using the ROC curve based on Youden's index, the eGFR cut-off was found to be 70 mL/min/1.73 m2 for patients with eGFR ≥60 mL/min/1.73 m2. eGFR is also an important risk factor in patients with eGFR 60-70 mL/min/1.73 m2. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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