| Abstrakt: |
Background: Fetal growth restriction (FGR) poses challenges in antenatal care due to its association with adverse perinatal outcomes. The cerebroplacental ratio (CPR), derived from Doppler ultrasound measurements, has emerged as a potential marker for evaluating fetal well-being in FGR pregnancies. Aim and Objective: To assess the predictive value of CPR in identifying adverse perinatal outcomes in suspected FGR cases. Materials and Methods: Conducted at Jaipur Golden Hospital, New Delhi, from July 2018 to May 2019, the study included 80 pregnant women with clinical suspicion of FGR, singleton pregnancies, and gestational age over 30 weeks. Doppler studies evaluated the umbilical artery pulsatility index (UA PI) and middle cerebral artery pulsatility index (MCA PI) to calculate CPR. Perinatal outcomes were analyzed, including delivery mode, birth weight below the 10th percentile, APGAR score < 7 at 5 minutes, neonatal interventions, and neonatal intensive care unit (NICU) admission > 24 hours. Statistical analysis employed sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) (p < 0.05). Results: 47.5% had CPR < 1, and 52.5% had CPR = 1. CPR significantly correlated with adverse perinatal outcomes (p < 0.001). It outperformed UA PI and MCA PI, with a sensitivity of 97.6%, specificity of 91.8%, PPV of 93%, and NPV of 97.1%. Conclusion: CPR is valuable in predicting adverse perinatal outcomes in suspected FGR pregnancies, surpassing UA PI and MCA PI in diagnostic accuracy. Further validation and optimization are necessary for managing high-risk pregnancies. [ABSTRACT FROM AUTHOR] |
