Nurturing the Mind from Within: Exploring the Role of Gut– Microbiota–Brain Axis in Postpartum Depression.

Autor: Rai, Srinidhi, Alva, Priya, Naresh, Sriram
Předmět:
Zdroj: Journal of South Asian Federation of Obstetrics & Gynecology; May/Jun2024, Vol. 16 Issue 3, p285-288, 4p
Abstrakt: The pathophysiology of postpartum depression (PPD) mostly involves disruptions of the immunological system, gut microbiota, neurotransmitters, hormone production, and neuroendocrine regulation. This review explores the reciprocal exchange of signals along the gut–brain axis, with a particular emphasis on the role that gut microorganisms play in neurotransmitter synthesis, precursor generation, and the secretion of vital metabolites, thus unravelling the complex interactions of the microbiota–gut–brain axis to pave a better understanding of microbiota-mediated pathogenesis, avenues for therapeutic possibilities leveraging microbiota–gut–brain axis modulations. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index