Enteric glia as friends and foes of the intestinal epithelial barrier function.

Autor: Bali, Vedrana, Grubisic, Vladimir
Předmět:
Zdroj: Frontiers in Immunology; 2024, p1-6, 6p
Abstrakt: This article explores the role of enteric glia in the function of the intestinal epithelial barrier. The gut lining acts as a barrier, allowing nutrients to pass through while keeping out pathogens. Increased permeability of the intestinal barrier, known as "leaky gut," has been linked to various gastrointestinal and extraintestinal disorders. Enteric glia, which are present in all layers of the gut, play a crucial role in regulating the gut epithelial barrier function. They can regulate ion and fluid transport in the intestine and may contribute to the treatment of functional diarrheal diseases. However, their specific biological functions are not fully understood, and further research is needed to understand their mechanisms and interactions. Enteric glia have also been implicated in various disorders, including Parkinson's disease and psychiatric disorders. The document provides a list of references that explore the structure, function, and interactions of enteric glial cells, as well as their involvement in different conditions and processes in the gastrointestinal tract. [Extracted from the article]
Databáze: Complementary Index