| Autor: |
Wang, Zhuang, Liu, Yuxiu, Song, Hongjian, Wang, Qingmin |
| Předmět: |
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| Zdroj: |
Green Chemistry; 6/21/2024, Vol. 26 Issue 12, p7419-7423, 5p |
| Abstrakt: |
We have developed a straightforward electrochemical protocol for direct α-amidation and α-pyrazolation of N-alkoxy- and N-aryloxycarbonyl pyrrolidines with amides or pyrazoles. Unlike previously reported methods, this protocol does not require pre-prepared amidation reagents, thereby shortening the synthesis route and boosting atom economy. Various functional groups are tolerated, and the reaction proceeds at room temperature in only 2.5 h without assistance from chemical oxidants or catalysts. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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