Autor: |
Fernández-Ruiz, Mario, García-Ríos, Estéfani, Redondo, Natalia, Rodríguez-Goncer, Isabel, Ruiz-Merlo, Tamara, Parra, Patricia, Sandonis, Virginia, López-Medrano, Francisco, Juan, Rafael San, González, Esther, Polanco, Natalia, Andrés, Amado, Navarro, David, Aguado, José María, Pérez-Romero, Pilar |
Předmět: |
|
Zdroj: |
Journal of Infectious Diseases; 6/15/2024, Vol. 229 Issue 6, p1812-1816, 5p |
Abstrakt: |
We measured cytomegalovirus (CMV)-specific antibodies that neutralize epithelial cell infection (CMV-AbNEIs) in 101 CMV-seropositive kidney transplant recipients (KTRs) at baseline and posttransplant months 3 and 6. All the patients received antithymocyte globulin and 3-month valganciclovir prophylaxis. There were no significant differences in pretransplant AbNEIs titers between KTRs that developed or did not develop any-level CMV infection or the composite of high-level infection and/or disease. One-year CMV infection-free survival was comparable between KTRs with or without pretransplant CMV-AbNEIs. No differences were observed by months 3 and 6. We observed no protective role for CMV-AbNEIs among CMV-seropositive KTRs undergoing T-cell–depleting induction. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
|