Rhodium-Catalyzed Direct Vinylene Annulation of 2-Aryloxazolines and Cascade Ring-Opening Using a Vinyl Selenone.

Autor: Kitano, Junya, Nishii, Yuji, Hirano, Koji, Miura, Masahiro
Předmět:
Zdroj: Synlett; Jul2024, Vol. 35 Issue 11, p1265-1268, 4p
Abstrakt: This article, published in the journal Synlett, discusses a study on the development of a rhodium-catalyzed direct vinylene annulation reaction. The researchers focused on using vinyl selenones as vinylene-transfer reagents and successfully demonstrated a three-component reaction to construct isoquinolone scaffolds. The article includes a table showing the optimization of reaction conditions. The study also explored the scope and limitations of the reaction system, proposing a mechanism for the coupling reaction and concluding that further optimization is needed. [Extracted from the article]
Databáze: Complementary Index