| Abstrakt: |
Background: Obstructive sleep apnea (OSA) is a condition marked by recurrent total or partial collapses of the upper airway during sleep, which result in obstructive apneas, hypopneas, and/or respiratory effort-related arousals. The aim of the present study was to predict outcome of OSA surgery by Neutrophillymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR). Methods: This clinical trial study included 24 adult patients with obstructive sleep apnea who conducted at Otorhinolaryngoloy Department of Zagazig University Hospitals. The patients' clinical and demographic data including age, sex, body mass index, predisposing factors and comorbid condition were noticed OSA and differential blood count were obtained before and after surgery. Results: There is significant higher value of WBCs, Lymphocyte, Neutrophil of severe obstructive apnea compared to moderate obstructive apnea p<0.05 before treatment. There is significant lower value of PLT, PLR of severe obstructive apnea compared to moderate obstructive apnea p<0.05 before treatment. But there was insignificant change of WBCs, Lymphocyte, PLR P>0.05. Whereas WBCs, neutrophil, lymphocyte, PLT, NLR, PLR significantly improved after treatment severe obstructive sleep apnea patients. There is significant and inverse relation between Apnea hypopnea index with lymphocyte, PLT, age. There is significant and direct relation between Apnea hypopnea index with NLR, WBCs, neutrophil. Conclusion: PLR could be considered a new inflammatory marker for inflammation in OSA patients, as it is a quick, cheap, and easily measurable property on routine CBC analysis. [ABSTRACT FROM AUTHOR] |
