Study Results from Samara State Medical University Broaden Understanding of Regenerative Medicine (Formation of Osteoconductive Biograft With Bioorganic Scaffold, Human Mesenchymal Stromal Cells, and Platelet-rich Plasma With Its Evaluation In...).

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Zdroj: Hematology Week; 6/18/2024, p581-581, 1p
Abstrakt: A study conducted at Samara State Medical University in Russia explored the use of a complex biograft for repairing bone defects. The researchers focused on the potential of platelet-rich plasma (PRP) to promote the proliferation and differentiation of mesenchymal stromal cells into osteoblasts. They evaluated the viability and adhesion of these cells in different bioorganic scaffolds and found that the scaffold based on xenogeneic collagen sponge had the least cytotoxicity. The study also demonstrated that allogeneic PRP positively influenced cell proliferation and osteogenic differentiation. The researchers concluded that the developed complex biograft showed biocompatibility and osteoconductivity, making it a potential option for regenerative medicine and reconstructive surgery of bone defects. [Extracted from the article]
Databáze: Complementary Index