| Abstrakt: |
A recent study conducted by researchers at JSS Academy of Higher Education and Research in Mysuru, India, has explored the use of lipid nanoparticles as a potential solution to the poor bioavailability of bromocriptine, a drug used in the treatment of Parkinson's disease. The researchers developed and evaluated bromocriptine-loaded solid lipid nanoparticles (BCR-SLN) and bromocriptine-loaded nanostructured lipid carriers (BCR-NLC) using the Box-Behnken design. The optimized lipid nanoparticles showed improved bioavailability and therapeutic efficacy of bromocriptine in the management of Parkinson's disease. This research suggests that lipid nanoparticles could be a promising carrier for enhancing drug penetration and improving the effectiveness of bromocriptine. [Extracted from the article] |
