| Abstrakt: |
A recent study conducted by researchers in the Department of Chemistry focused on the characterization of degradation products of the drug gilteritinib. The study utilized liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify seven distinct degradation products formed under various stress conditions. Additionally, the researchers developed a stability-indicating high-performance liquid chromatographic (HPLC) method to accurately determine gilteritinib in the presence of impurities. The method was validated through LC-MS/MS, confirming its efficacy in evaluating process-related impurities and stress degradation products of gilteritinib. For more information, the full article can be accessed through the provided link. [Extracted from the article] |
